Spilling The Green Tea

With the exception of identical twins, every single person’s DNA is unique; that is how God designed us.

With that in mind, what is beneficial to one person may not be so beneficial to another person. It is important to know your own body and what it needs to run efficiently. You wouldn’t put the wrong type of gas in your car, right?

Some of you may have heard of Gary Brecka, a biologist, biohacker and longevity expert. He is well-known in the naturopathic and holistic circles as he promotes lifestyle changes that harness the healing properties of nature. He is anti-Big Pharma. He doesn’t preach the status-quo but instead keeps it real and tells you the real truth when it comes to our health.

I follow him on Facebook and Instagram so one day I was scrolling through his videos and came across one particular video where he discussed what every person on this planet should do if they want to prioritize their health.

The very FIRST one was to take a DNA methylation test. Methylation, when it involves DNA, is defined as: methylation involves adding a methyl group to a cytosine base, often at specific locations called CpG islands. This can affect gene expression by either turning genes “on” or “off”. 

I first personally touched on this topic in my post, “MTHFR: The Gene Mutation And Its Impact“. I discussed what the MTHFR gene is and how a mutated MTHFR gene can impact health. I revealed that I tested positive for a DOUBLE MTHFR gene mutation and this impacts how my body processes folate (B9), a vitamin responsible for cell growth, healthy red blood cells, and amino acid metabolism.

As a side note, I have been diagnosed with an underactive thyroid and the doctor immediately put me on Levothyroxine, which hasn’t done anything and, from what I learned, is pretty useless and can actually damage your thyroid. My symptoms have included fatigue, bloating, and a slower metabolism.

I assume these symptoms have to do with my metabolic panel and hormones and were the reasons for my interest in these gene mutations as they may be the culprit to my symptoms.

A DNA methylation test not only tests for the MTHFR gene mutation, but other genes as well. Here is a list of the genes tested and their roles:

• COMT – brain
• VDR – Vitamin D
• CBS – sulfur
• MTR – amino acids
• BHMT – liver
• SHMT – cells
• AHCY – cells
• ACAT – cells
• MAO A – brain
• MTHFD1 – folate
• NOS3 – blood vessels
• MAT1A – cells
• MTHFR – folate

With all the technology we have, we still don’t have the ability to alter our genes; we have what we have. But Gary Brecka says that if you test positive for any of these mutated genes, you will need to supplement for its function. He states:

“When you look at the genes of methylation, I look at five major and a few minors, when you look at the genes of methylation, these are the genes that code for how materials are taken into the body are refined into usable form. And these are not mutations that you’re going to suffer from. What they do is they cause deficiencies to arise in the body and its this deficiency that leads to the expression of these conditions. If you have a broken gene and you simply supplemented for their deficiency, my hypothesis is it would get you 85%-90% of the way to where you want to be and it would pull so many anchors up off your stern. It would be absurb! Anxiety, anxiousness, ADD, ADHD, OCD, manic depression, bipolar, poor gut issues, poor sleep, waking mind, poor focus and concentration; these all come from a lack of very specific nutrients in your body and most of us do not have a clean enough diet and a clean enough fuel sources like the water we’re drinking, to get there without supplementation. I believe everybody should be on a good methylated multivitamin; meaning, don’t worry whether or not your body can break something down into the usable form; feed it the usable form.”

A DNA mehtylation test is a one time test; once you know your results that is it, nothing will change over the years. And once you know, you can alter your lifestyle accordingly.

So I decided to take one of these tests. I ordered my kit from LifeDNA and bought the “methylation genes report with DNA kit”. It cost me $219 which is pricey, BUT if it means that I can feel better and be overall healthier and it’s a one time fee, I believe it is worth it.

It arrived quickly in the mail.

It comes with your own unique activation code which you will use to create your account online so that when the test is received and analyzed you will be notified and your results uploaded. All it took was a simple swab of the inside of my cheek; nothing invasive. Then you just mail it back in the prepaid envelope.

It does take 3-5 weeks to get your results, and it did take about 5 weeks to get an email stating my results were in!

Today, July 8th, 2025 is when I discovered how many methyl cycle genetic variants I have.

Out of 12 tested, I have 10 that came back as strong genetic variants.

Below I will be breaking down each of those 10 variants and how they could be impacting my own health. It may be a LOT to read but it is so beneficial for anyone to know this as you will NEVER hear a medical doctor talk about this. I would bet money that most doctors don’t even know anything about methylation and gene variants; they pretty much only know how to treat symptoms. So here are the genetic variants flagged on my personal report:

CBS – MEDIUM RISK

About: The CBS gene is responsible for making cystathionine beta-synthase enzyme. Homocysteine and serine are converted to cystathionine by this enzyme using pyridoxine, a Vitamin B6 derivative. Antioxidants taurine or glutathione can be produced via this transsulfuration process, which is an essential process for the production of cysteine-containing amino acids. Cysteine-containing amino acids are important for protein structure, antioxidant activity, detoxification, and metabolic function.

About Your Result: Studies have shown that individuals with one or more of these CBS risk variant(s) may be at a higher risk of homocysteine and cystathionine imbalance, and elevated levels of homocysteine. Increased homocysteine levels are potentially an indicator of cardiovascular problems. High homocysteine levels have also been linked to an increased risk of Alzheimer’s disease and other forms of dementia. High levels of homocysteine can contribute to Osteoporosis, associated with weakened bones and increased risk of fractures.

Ingredient Suggestions:

• Pyridoxal-5-Phosphate (15mg) – Active B6 : Vitamin B6 is readily available in a variety of both animal and plant-based sources, making it less likely to be deficient when you maintain a diverse diet. Inadequate levels of this essential nutrient can also manifest when there’s a shortfall in other B vitamins, like Vitamin B9 and Vitamin B12.
• Methylfolate – Active B9 (1mg): Vitamin B9, folate, is a water-soluble vitamin that is critical in maintaining cognitive function. Best time to take: Before breakfast, into empty stomach

Actionable Suggestions:

• Preliminary studies suggest that black and green tea, cinnamon, garlic extract, ginger, and soy could significantly reduce homocysteine levels. Clinical trials in humans have shown curcumin and resveratrol with favorable effects.
• Include a regular exercise regimen to maintain your fitness to help potentially mitigate any cardiovascular or bone strength concerns associated with potentially higher homocysteine levels.
• Make sure to support your body’s methylation process by consuming foods high in B9, B12, and B6. You can obtain these B vitamins from green leafy vegetables, legumes, animal products, and nuts and seeds.

COMT – HIGH RISK

About: COMT is an important enzyme for the metabolism of various catecholamines (neurohormones responsible for the fight-or-flight response of the body) such as dopamine, epinephrine, and norepinephrine. Variations in COMT can cause hypothalamic-pituitary-adrenal (HPA) axis dysfunction and elevated levels of cortisol, which can affect the body’s ability to handle stress.

About Your Result: Individuals with COMT risk variant(s) may exhibit a decrease in normal enzyme activity. The enzyme activity could further decrease with the more risk variants carried. People with COMT risk variant(s) have been reported to experience strong emotions towards stress and may be less able to handle negative events well. The COMT risk variant(s) may contribute to higher dopamine levels than those without the risk variants. Some studies have shown that higher dopamine levels may negatively impact prefrontal neural signaling. The COMT risk variant(s) has also been associated with an alteration in estrogen metabolism. Some studies have shown that certain alterations in estrogen metabolism may lead to an increased risk of infertility. Interestingly, those with the risk variants may have a better working memory than those without the risk variants.

Ingredient Suggestions:

• Magnesium 2000 mg (144 mg elemental magnesium): Magnesium, an important element in the body, is found naturally in several plants, added to many food products, and included in some medications, including antacids and laxatives. Best time to take: Before sleep Interactions: High doses of Magnesium supplement can interfere with Zinc absorption.

Actionable Suggestions:

• Incorporate phytonutrient-rich foods such as onions, garlic, celery, and grapefruit to further potentially support hormonal balance.
• To manage and optimize estrogen levels, look to include cruciferous vegetables like broccoli, cabbage, and Brussels sprouts in your diet. These vegetables may help support the liver in detoxifying excess estrogen, crucial for maintaining hormonal balance.
• Conduct detailed blood work to evaluate your methylation cycle and determine the optimal form of Vitamin B12 (hydroxy, adenosyl, or cyano) that is best tolerated by your body.
• Individuals with a COMT (+) variant should carefully manage their intake of methyl donors, as excess can exacerbate symptoms.

MAO-A – MEDIUM RISK

About: MAO-A is a gene responsible for creating an enzyme known to be involved in the breaking down of certain neurotransmitters (serotonin, norepinephrine, and dopamine). Variations in the MAO-A gene can lead to alterations in the activity of the enzyme it encodes. This enzyme is found in the outer membrane of the mitochondria in nerve cells and has been studied in conjunction with the regulation of mood, emotion, and behavior. MAO-A variants may be more commonly detected in males compared to females. This risk variant may be associated with emotional disturbances such as aggressive and antisocial behaviors. It has been dubbed the “Warrior Gene.”

About Your Result: Individuals with MAO-A risk variant(s) may have decreased MAO-A enzyme levels, which may result in higher levels and slower breakdown of serotonin, dopamine, and norepinephrine. Some studies have linked MAO-A risk variant(s) to aggression, impulsivity, and mood disorders. The risk variant(s) have also been studied in conjunction with people being more susceptible to aggressive and antisocial behavior.

Ingredient Suggestions:

• Riboflavin-5-Phosphate – Active B2 (30mg): Vitamin B2, also called riboflavin, helps the body to convert food into fuel to produce energy. It is a key cofactor for the MAO-A enzyme.

Actionable Suggestions:

• With guidance from your physician, include riboflavin rich foods in your diet such as eggs, meat, green leafy vegetables, and dairy products (subject to any food intolerances you may have) to potentially naturally boost levels of this riboflavin.
• Discuss with your physician the possibility of supplementing with riboflavin, especially if you might be experiencing symptoms related to its deficiency or issues related to MAO-A functionality.
• Consider increasing your intake of Vitamin B2 (Riboflavin), as it is a key cofactor for the MAO-A enzyme and may help support its proper function. Riboflavin is essential for numerous biological processes and can aid in the enhancement of MAO-A activity, which is important for managing neurotransmitters in the brain.

MAT1A – MEDIUM RISK

About: The MAT1A gene is responsible for encoding the enzyme methionine adenosyltransferase isoform type-1, which is primarily expressed in the liver. This enzyme is crucial for converting methionine to S-adenosylmethionine (SAMe), a key methyl donor involved in one-carbon metabolism and methylation reactions throughout the body. SAMe is essential because it donates methyl groups to a wide range of molecules, influencing DNA and RNA methylation, neurotransmitter synthesis, lipid metabolism, and detoxification processes. Disruptions in the MAT1A function can lead to lower SAMe levels, higher methionine, and slightly higher homocysteine levels linking it to cardiovascular and neurodegenerative diseases.

About Your Result: Individuals with MAT1A risk variant(s) may potentially exhibit disruptions in MAT1A enzyme function. People with MAT1A risk variant(s) may experience lower SAMe levels. Lower SAMe levels may not be ideal since this molecule is a key methyl donor in several methylation reactions in the body. Individuals with MAT1A risk variant(s) may also experience higher homocysteine levels. Too much homocysteine in the body can become toxic. Studies show that people with MAT1A risk variant(s) may have a higher likelihood of cardiovascular risks such as hypertension and stroke.

Actionable Suggestions:

• To support MAT1A’s function in producing sufficient SAMe, you may consider supplementing with magnesium (cofactor for ATP production) and zinc (for MAT1A stability).
• Ask your doctor if supplementing directly with SAMe may be helpful for you. Typical doses are usually 200-800 mg/day, and the best forms are usually SAMe Tosylate or SAMe Disulfate Tosylate. This supplement can be overstimulating in some people, so start low.
• To support higher homocysteine levels, you may consider supplementing with Folate (Vitamin B9), Cobalamin (Vitamin B12), and Riboflavin (Vitamin B2).

MTHFD1 – HIGH RISK

About: The MTHFD1 gene encodes an enzyme of the same name (MTHFD1). The enzyme MTHFD1 is known as a trifunctional enzyme that is important for generating and interconverting 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine (an essential amino acid), thymidylate (an essential precursor for DNA biosynthesis), and de novo purine synthesis (a biochemical pathway that creates purine nucleotides from simple molecules). This gene, along with MTHFR, are important enzymes in folate metabolism.

About Your Results: People with the MTHFD1 risk variant(s) gene may be at a higher risk of imbalance in folate metabolism. Folate metabolism is important for cardiovascular health, pregnancy, among other health concerns. Some studies have shown the MTHFD1 risk variant(s) to contribute to excessive levels of homocysteine in the blood, and slightly decreased levels of methionine. Increased homocysteine has been observed in studies to be toxic to cells and potentially be an indicator for cardiovascular problems when levels are elevated. Lower levels of methionine have been studied in conjunction with impaired immune function, increased susceptibility to infection, and impaired wound healing. Methionine deficiency can also lead to a decrease in levels of S-adenosylmethionine (SAM), which is an important molecule involved in methylation reactions and the regulation of gene expression. It is important for those with the MTHFD1 risk variant(s) to be mindful of their choline intake, as they may not be getting enough.

Ingredient Suggestions:

• Phosphatidyl Choline (500mg): Choline is an essential nutrient that plays important roles in modulating gene expression, cell membrane signaling, lipid transport and metabolism, and early brain development. In addition, supplementation of choline was shown to have favorable effects on several physiologic outcomes during pregnancy, including placental functioning and the fetal response to stress. Best time to take: Before meal.

Actionable Suggestions:

• Look to ensure optimal cardiovascular fitness through consistent cardiovascular exercise.
• To help potentially reduce homocysteine levels, incorporate choline-rich foods into your diet, which can be beneficial for individuals with variants in the MTHFD1 gene. Foods high in choline include egg yolk, beans, tofu, and various meats, all of which can contribute to lowering homocysteine, a risk factor for various conditions.
• Discuss with your doctor the benefits of increasing your intake of folate and activated Vitamin B12 to support the functions related to the MTHFD1 gene. Include foods rich in these nutrients, such as spinach, kale, meat, and nuts (subject to any food intolerances you may have), in your diet or consider supplementation as recommended by your healthcare provider

MTHFR – HIGH RISK

About: The MTHFR gene is responsible for providing instructions for making methylenetetrahydrofolate reductase enzyme, which helps the body process folate (Vitamin B9). Folate is needed for healthy red blood cell formation and is crucial during pregnancy for fetal development. MTHFR is involved in the process of converting homocysteine to methionine that the body can use for building proteins. MTHFR gene variants can cause elevated homocysteine levels. Homocysteine has been observed in studies to be toxic to cells and potentially be an indicator for cardiovascular problems when levels are elevated.

About Your Results: Individuals with MTHFR risk variant(s) may exhibit a decrease in normal enzyme activity. The enzyme activity could further decrease with the more risk variants carried. People with risk variant(s) in this gene may have elevated levels of homocysteine in blood plasma compared to those without the risk variant. Increased homocysteine levels have been observed in studies to be toxic to cells and potentially be an indicator for cardiovascular problems. People with MTHFR risk variants have been reported to be more susceptible to altered levels of DNA methylation compared to those without the risk variants. Women who are pregnant or planning to become pregnant should speak to their physician or other healthcare provider about their MTHFR results, as processing folate properly is important for fetal development.

Ingredient Suggestions:

• Active B9 (Methylfolate) (1mg): Vitamin B9, folate, is a water-soluble vitamin that is critical in maintaining cognitive function. Best time to take: Before breakfast, empty stomach

Actionable Suggestions:

• Look to maintain improved cardiovascular fitness to help potentially mitigate cardiovascular concerns associated with higher homocysteine levels
• Better gut wellness can support overall well-being and can help in the more effective utilization of nutrients critical for individuals with the MTHFR variant.
• Incorporate gut-healthy foods such as fermented products and broths into your diet to improve gut wellness and potentially enhance nutrient absorption.
• Monitor your homocysteine levels. A blood test provided by your healthcare provider should assist with monitoring.
• Discuss with your healthcare provider the potential benefits of supplementing with Folate (Vitamin B9) and Cobalamin (Vitamin B12) to support methylation processes affected by the MTHFR variant. A consultation can determine the best form of supplementation, possibly suggesting L-methylfolate over synthetic folic acid due to its higher bioavailability and ability to be absorbed by those with MTHFR risk variants.

MTR AND MTRR – HIGH RISK

About: MTR gene is responsible for encoding the MTR (methionine synthase) enzyme, which converts homocysteine to methionine using vitamin B12. Methionine is an essential amino acid that is important for building proteins in the body. Homocysteine is an amino acid produced during the breakdown of proteins; it has been observed in studies to be toxic to cells and potentially be an indicator for cardiovascular problems when levels are elevated. To function properly, MTR enzyme requires an MTRR (methionine synthase reductase) enzyme for its activation.

About Your Results: Some studies have shown the risk variant(s) in the MTR and/or MTRR gene to be associated with problems in methylcobalamin utilization and methionine biosynthesis. Methylcobalamin is a form of Vitamin B12; one of its primary functions is to act as a coenzyme in the conversion of homocysteine to methionine, known as methionine biosynthesis. Individuals with risk variant(s) may be at risk of lower B12 levels since the MTR enzyme is utilizing B12 at a faster rate. Vitamin B12 has been shown to be important for: DNA synthesis and cell division, red blood cell formation, energy production, mood regulation, and other important bodily functions. Those with the risk variant(s) may also exhibit higher homocysteine levels, especially if B12 levels are low. Some studies have shown higher homocysteine levels to potentially be an indicator for cardiovascular problems.

Ingredient Suggestions:

• Active B12 (Methylcobalamin, Adenosylcobalamin, Hydroxocobalamin) (1mg): Vitamin B12 is a water-soluble vitamin that is required for the development and maintenance of brain, spinal cord, and nerve cells, and is consequently vital in normal neurological function. It is also used during myelin formation, which protects the nerves. Best time to take: Before breakfast, empty stomach

Actionable Suggestions:

• Consider enhancing your diet with foods rich in Vitamin B12 or exploring supplementation options to support adequate B12 levels. Certain risk variants in other methylation genes may impact which version of Vitamin B12 is best for you.
• Look into a blood test for your homocysteine levels from your healthcare provider.
• Pay attention to homocysteine levels, especially if Vitamin B12 levels are low, as those with risk variants may exhibit higher levels. Elevated homocysteine has been associated with an increased risk of cardiovascular issues.
• Individuals with risk variants in the MTR and MTRR genes might experience faster utilization of Vitamin B12, potentially leading to lower levels. Regular monitoring of Vitamin B12 is suggested due to its importance in DNA synthesis, cell division, red blood cell formation, energy production, and mood regulation.

NOS3 – MEDIUM RISK

About: The Nitric oxide synthase 3 (NOS3) gene produces an enzyme responsible for the production of nitric oxide (NO) and is predominantly expressed in the endothelial tissue, which lines the circulatory system and heart. Nitric oxide plays a protective role in the cardiovascular system and acts as a vasodilator which allows the smooth muscle tissue to relax.

About Your Results: Individuals with risk variant(s) in the NOS3 gene are reported to have lower NOS3 enzymatic activity. Some studies have associated the NOS3 risk variant(s) with cardiovascular problems such as hypertension. People with NOS3 risk variant(s) may also have difficulty breaking down ammonia and generating nitric oxide, leading to accumulation of ammonia in the body. Excess ammonia can lead to symptoms like confusion and lethargy, among others. Moreover, the NOS3 risk variant(s) has also been linked to higher susceptibility to metabolic syndrome.

Ingredient Suggestions:

• Omega 3 Fatty Acids (1500mg): Omega-3 is a group of nutrients that is essential for heart health. It usually contains DHA and EPA that are known to reduce blood pressure and triglycerides, and increase good cholesterol in the body. Best time to take: after breakfast

Actionable Suggestions:

• Consult with your healthcare professional about the potential benefits of taking antioxidant supplements like Vitamin C. Antioxidant supplements may help neutralize free radicals, which could be particularly beneficial if the NOS enzyme is compromised. Look to potentially add other antioxidants into your diet to help combat oxidative stress.
• Engage in regular physical activity, which can improve nitric oxide release. Exercise is beneficial for managing hypertension and enhancing overall cardiovascular wellness. Focus on Zone 2 Cardio, 60-70% of your maximum heart rate, to potentially help increase your aerobic capacity.
• If you are at risk for cardiovascular disease due to elevated blood pressure, consider reducing your sodium intake. Speak with your healthcare provider about the appropriate level of sodium reduction for your specific health needs.
• Discuss with your healthcare professional the benefits of consuming foods rich in omega-3 fatty acids. Include omega-3 sources in your diet such as fish, chia seeds, tofu, and avocado (subject to any food intolerances you may have) to potentially improve your blood lipid panel and decrease your risk of hypertension.

SHMT1 – MEDIUM RISK

About: SHMT1 gene is responsible for making an enzyme that plays a vital role in the folate metabolism pathway. The folate metabolism pathway is important for the synthesis of DNA, RNA, and proteins, the production of red blood cells, and the metabolism of homocysteine. The enzyme created by SHMT1 catalyzes the interconversion of serine and tetrahydrofolate to glycine and 5,10-methylenetetrahydrofolate, respectively. The production of these metabolites leads to the synthesis of the building blocks of DNA (thymidine and purines).

About Your Results: People with SHMT1 risk variant(s) may be at a higher risk of alterations in gene methylation and DNA synthesis. Gene methylation and DNA synthesis are important for gene expression and cellular function. Some studies have shown individuals with SHMT risk variant(s) may exhibit a higher likelihood of inadequate methyl-folate generation. Methyl-folate generation is a critical step in the folate metabolism pathway, which is responsible for the synthesis of DNA, RNA, and proteins. Folate metabolism is important for women who are pregnant or planning to become pregnant. Please speak with your doctor about folate supplementation if you are pregnant or planning to become pregnant.

Actionable Suggestions:

• Avoid alcohol and cigarettes to decrease the risks of neural tube defects (NTD) and DNA aberrations. These lifestyle choices may significantly impact overall wellness, particularly in individuals with genetic susceptibilities like those involving the SHMT1 gene.
• Include pyridoxine-rich foods in your diet, such as legumes, tofu, salmon, potatoes, and pistachios (subject to any food intolerances you may have), to support overall wellness and methylation processes.
• Consuming folate-rich foods such as spinach, kale, leek, broccoli, and legumes (subject to any food intolerances you may have) can enhance your folate levels naturally.
• Increase your consumption of Folate (Vitamin B9) and Pyridoxine (Vitamin B6) through diet or supplements to help mitigate risks associated with inadequate methy-folate generation.

VDR – MEDIUM RISK

About: The VDR gene is responsible in providing instructions for making Vitamin D receptors for the bioactive form of vitamin D, calcitriol. Calcium absorption from food also requires Vitamin D, which supports the function of the heart, muscles, and bones.

About Your Results: Studies have shown that individuals with VDR risk variant(s) may exhibit a decrease in normal vitamin D receptor function. Since the VDR gene is responsible for the body’s ability to respond to Vitamin D, the presence of risk variant(s) may increase the risk of having bone-related problems. VDR regulates some metabolic pathways related to the immune response. Studies have shown that individuals with risk variant(s) in this gene may have a higher risk of having an impaired immune response as a result. In some studies, the VDR Taq variant has been linked to lower dopamine levels compared to those without the risk variants. Lower dopamine levels have been associated with feeling anxious, moody, depressed, and unmotivated. The VDR Fok variant has been linked to blood sugar regulation and pancreatic function.

Ingredient Suggestions:

Vitamin D3 (30mcg): Vitamin D exists in two main biological forms — D2 (ergocalciferol) and D3 (cholecalciferol). Typically, D2 comes from plants, and D3 comes from animals. According to studies, Vitamin D3 (cholecalciferol) is more effectively absorbed than D2, so D3 is the recommended form, especially if you’re not following a vegetarian or vegan diet. Best time to take: After breakfast

Vitamin K2 (100mcg): Vitamin K2, in the form of menaquinone-7 (MK-7) was associated with improved bone strength and overall bone health. Best time to take: After breakfast Interactions: Excess vitamin A can decrease the bioavailability of vitamin K. Vitamin A’s upper limit is 900 mg, taking this amount or more on a regular basis may have a negative impact on vitamin K absorption.

Actionable Suggestions:

• Herbal supplements like ginkgo biloba and mucuna pruriens (velvet bean) may enhance dopamine levels, supporting brain wellness and mood regulation.
• Supplementing with methylcobalamin, or methyl-B12, can be beneficial, especially for those with the VDR (+) variant who can tolerate methyl donors well. Those without the risk variant (-/-) should be cautious with the methyl form of B12 and consider alternative forms or dosages
• Consider reducing your caffeine intake as it may inhibit calcium absorption. Decreasing caffeine can prevent potential deficiencies and malabsorption issues, potentially supporting stronger bone density and overall wellness.
• Aim for adequate sun exposure to naturally boost your body’s vitamin D production.
• Potentially enhance your calcium intake through dairy products, nuts and seeds, sardines, and legumes which may support bone wellness and overall wellness.
• Incorporate foods high in vitamin D such as nuts and seeds, egg yolks, and fatty fish into your diet, dependent on any food intolerances you may have
• To address the potential risks associated with VDR gene variants, consider supplementing with vitamin D to promote optimal levels.

NORMAL MARKERS

After all that, I did have two markers that came back normal so just for informational purposes here is what they are:

ACAT

ACAT About: The ACAT gene provides instructions for making an enzyme that is found inside the mitochondria of the cell, known as acetyl-CoA acetyltransferase (ACAT), which helps break down proteins and fats from the diet. This enzyme is involved in the breakdown of fatty acids in the body, specifically in the process of ketone body synthesis. Ketone bodies are important sources of energy for the body, particularly during periods of fasting or low carbohydrate intake. Mutations in the ACAT gene can potentially lead to deficiencies in ACAT activity and disruptions in ketone body metabolism.

ACAT Result: This is great! You may have a normal ACAT enzyme function which may lower your risk for inflammation, weight gain that could result in obesity, and insulin resistance. Continue incorporating antioxidant-rich food such as citrus fruits, avocado, carrots, garlic, tea, herbs, and spices to increase the protection of cells from free radicals.

AHCY

About: AHCY gene is responsible for the production of the enzyme S-adenosylhomocysteine hydrolase involved in a multi-step process of methionine (an amino acid) breakdown. Because of this enzyme, the methionine cycle can produce adenosine (an essential molecule for DNA production) for nucleotide biosynthesis, which is the process of creating the building blocks of DNA. It is crucial to have methionine be properly broken down to avoid hypermethioninemia, or the excessive levels of methionine. Moreover, some studies have shown S-adenosylhomocysteine hydrolase turnover may be essential for the body to cope with oxidative stress or free radicals.

AHCY Result: This is great! You may have a normal AHCY enzyme function which may prevent you from having too much methionine (hypermethioninemia). Continue supporting your methylation cycle by incorporating folate, B12, and B6 -rich food such as meat, whole grains, and green leafy vegetables in your diet.

CONCLUSION

So what do I do now knowing this information? From what I can gather at the moment, it is imperative I start taking a methylated multi-vitamin. Since my genes can’t methylate properly I need an already methylated vitamin.

I also highly encourage everyone to take this test; it’s a one-time test and to have this information about yourself is invaluable.

Click here to go to LifeDNA and select “Methylation Genes Report”. The plan (the one I bought) is “13 Methylation Genes Report + DNA Kit”.

I will be sure to post updates when available and am excited to give my body a much needed overhaul!

Remember knowledge is power!